Lavin's career began on Broadway in the late 1960s, where she quickly established herself as a talented performer. She transitioned to television in the 1970s, landing her breakthrough role as Alice Hyatt in the CBS sitcom Alice Doesn’t Live Here Anymore. The show, inspired by Martin Scorsese's film of the same name, followed Alice, a widowed mother working as a waitress at Mel's Diner in Phoenix, Arizona, to support her young son.
The sitcom, later shortened to Alice, became a cultural touchstone, resonating with working mothers across the country. Lavin's portrayal earned her widespread acclaim, including two Golden Globe Awards and a nomination for a third. The series ran successfully for nine seasons, concluding in 1985.
Beyond Alice, Lavin appeared in other television hits, including Barney Miller, and was a celebrated presence on the Broadway stage. She starred in several Neil Simon plays, such as Last of the Red Hot Lovers and Broadway Bound. Her work in the latter earned her a Tony Award, one of four nominations she received throughout her illustrious stage career.